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Unique Changes in the Incidence of Acute Chest Syndrome in Children with Sickle-Cell Disease Unravel the Role of Respiratory Pathogens: A Time-Series Analysis
Chest. 2023 Aug 4:S0012-3692(23)05256-X. doi: 10.1016/j.chest.2023.07.4219. Online ahead of print.ABSTRACTBACKGROUND: Acute chest syndrome (ACS) is a life-threatening complication of sickle-cell disease (SCD). Although respiratory pathogens are frequently detected in children with ACS, their respective role in triggering the disease is still unclear. We hypothesized that ACS incidence followed the unprecedented population-level changes in respiratory pathogens dynamics following the COVID-19-related non-pharmaceutical interventions (NPIs).RESEARCH QUESTION: What is the respective role of respiratory pathogens in ACS epidem...
Source: Chest - August 6, 2023 Category: Respiratory Medicine Authors: Zein Assad Zaba Valtuille Alexis Rybak Florentia Kaguelidou Andrea Lazzati Emmanuelle Varon Luu-Ly Pham Lea Lenglart Albert Faye Marion Caseris Robert Cohen Corinne Levy Astrid Vabret Francois Gravey Francois Angoulvant Berengere Koehl Naim Ouldali Source Type: research

Etiology of Acute Infectious Meningitis and Meningoencephalitis in Karachi, Pakistan: Retrospective Observational Study from a Tertiary Care Center
We report a broad range of pathogens causing ME in southern Pakistan and show a high burden of preventable illness. Synergistic actions to improve diagnostic strategies, increase vaccinations, and introduce measures to reduce water-borne and vector-borne diseases are required to reduce the ME burden in Pakistan and prevent future outbreaks.PMID:37460090 | DOI:10.4269/ajtmh.23-0182
Source: Am J Trop Med Hyg - July 17, 2023 Category: Infectious Diseases Authors: Sadia Shakoor Tazeen Fatima Fatima Mir Asima Shahid Najma Shaheen Erum Khan Bushra Jamil Source Type: research

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